Notably, F13-CTHRC1 was predicted to communicate with the tumor-enriched EN10-SERPINE1 and EN03-VWA1 endothelial cells through WNT5A-MCAM and LRP1-SERPINE1 interactions, both of which are highly expressed by these cell types and have been characterized as molecular switches for cell motility and angiogenesis [52, 53]. The gene discussed is CTHRC1; the disease is neoplasm.