We then used the risk score method to establish a risk signature for patients with AML based on the gene expression levels as follows: FA risk score = (0.299 * SLC25A1 expression) - (1.090 * MLYCD expression) - (0.394 * CYP4F2A expression) + (0.474 * PLA2G4A expression) + (0.488 * ACBD4 expression) + (0.538 * ACOT7 expression) + (0.566 * ACSF2 expression) + (0.632 * CBR1 expression) + (0.750 * ACSL5 expression). The gene discussed is PLA2G4A; the disease is acute myeloid leukemia.