In transgenic mice expressing simian virus 40 (SV40) oncogene, whole-body irradiation (WBI) followed by intravenous injection with T Ag-specific donor CD8+ T cells resulted in rapid, high-level T cell accumulation within the brain, CPC tumor elimination, persistence of T cells at tumor sites, and prevention of tumor recurrence [18, 19]. The gene discussed is AGT; the disease is neoplasm.