However, the mechanisms in AIP and AEP partly differ: it is necessary that actual activation of the effectors is inhibited in AIP and, consequently, actual action outcomes do not occur in AIP (Guillot, Di Rienzo, Macintyre, Moran, & Collet, 2012; Rieger, Dahm, & Koch, 2017). This evidence concerns the gene LGMN and autoimmune pancreatitis.