The genesincluded in this list include markers of HCC, such as glypican 3 (Gpc3)and α-feto protein (Afp), genes regulating cell proliferation,such as cyclin D1 (Ccnd1), p21 (Cdkn1a), and Ki-67 (Mki67), and genesregulating angiogenesis, such as Hif1a (Figure 6C). This evidence concerns the gene CDKN1A and hepatocellular carcinoma.