No significant collapsed areas in the follicular thyroid carcinoma. Increase in the number of apoptotic cells at 40 μg/L MC-LR.FT3 and FT4 were significantly decreased at 40 μg/L. TSH was significantly upregulated at 20 μg/L and 40 μg/L.Dio3 was significantly upregulated in skin and thyroid at 40 μg/L.MC-LR at 10, 20, and 40 μg/L induced phosphorylation of ERK, p38, and MAPK. Here, DIO3 is linked to thyroid gland follicular carcinoma.