A highly significant decline in white blood cells (WBCs), international normalized ratio (INR), prothrombin time (PT), platelets, and albumin levels (p < 0.001) and an increase in hemoglobin (HB), bilirubin, creatinine, and AFP levels (p < 0.001) were found in HCC patients. The gene discussed is F2; the disease is hepatocellular carcinoma.