Similarly, after conditioning on the stronger dominant effect of HLA-DRB1*15:01 in African Americans (dominant OR = 1.91, p = 3.48 x 10−05); although not meeting the stringent threshold of p < 1.00 x 10−03 for secondary signals, a residual association of HLA-DQB1*06:02 with MS risk remained (dominant OR = 1.25, p = 1.57 x 10−02). The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.