Besides, to illustrate that Andr can reduce myocardial hypertrophy by suppressing ER stress, we further treated cells with 10 μM of ER stress agonist TN + Ang II + 10 μM Andr and found that TN reverses the effect of Andr suppressed cardiac hypertrophy in vitro (Figure 4(B–D)). Here, AGT is linked to cardiac hypertrophy.