UBE2S and lung carcinoma: To understand the role of UBE2C/UBE2S E2 conjugating enzymes in the development of lung cancer, we first searched the cBioPortal database (https://www.cbioportal.org), which is generated largely based on The Cancer Genome Atlas (TCGA), to systematically analyze the genetic changes in the UBE2C and UBE2S genes in lung cancer samples.