To understand the role of UBE2C/UBE2S E2 conjugating enzymes in the development of lung cancer, we first searched the cBioPortal database (https://www.cbioportal.org), which is generated largely based on The Cancer Genome Atlas (TCGA), to systematically analyze the genetic changes in the UBE2C and UBE2S genes in lung cancer samples. Here, UBE2S is linked to lung cancer.