An in vitro study has found that COS with MW < 1 kDa (GO2KA1) may prevent hyperglycemia by inhibiting intestinal glucose digestion-related enzyme α-glucosidase and the transporters sodium-dependent glucose cotransporter (SGLT)-1 and GLUT2, and enhance glucose uptake, at least in part, by upregulating adiponectin expression through peroxisome proliferator-activated receptor (PPAR)-γ in adipocytes [57]. Here, ADIPOQ is linked to Hyperglycemia.