NFE2L2 and brain ischemia: To verify the effect of pharmacological activation of Nrf2, the commonly-used activator sulforaphane (SFN) was deployed in two well-known models of cerebral ischemia, i.e., in vitro —excitotoxicity injury in organotypic hippocampal slices; and in vivo -5-min bilateral carotid-artery occlusion in gerbils.