The pathways identified included gap junctions, signaling pathways regulating the pluripotency of stem cells, transforming growth factor (TGF)-β signaling, γ-aminobutyric acid (GABA)-ergic synapse, axon guidance, glioma, Wnt signaling, thyroid hormone signaling, toll-like receptor signaling, vascular endothelial growth factor (VEGF) signaling, Notch signaling, mammalian target of rapamycin (mTOR) signaling, Alzheimer’s disease, neurotrophin signaling, and glutamatergic synapse. The gene discussed is TG; the disease is early-onset autosomal dominant Alzheimer disease.