Serum levels of AST and ALT increased with the severity of hepatitis: AST (mean: non-severe HEV: 228 [49] vs. HEV w/o LD: 572 [679] vs. HEV w LD: 2424 [1996], p = 0.001) and ALT (median: 187 [230] vs. 1310 [1188] vs. 2819 [1094], p < 0.001), while levels of bilirubin (median: 1.7 [2.4] vs. 1.2 [2.8] vs. 9.4 [6.5], p = 0.002) and INR (mean: 1.2 ± 0.2 vs. 1.6 ± 0.2, p = 0.005) were higher, when comparing HEV w/o LD to HEV w LD. The gene discussed is GPT; the disease is Hepatitis.