PRPF40A and cryptococcosis: Because of the importance of Fbp4, Fbp11, and Fbp8 in development of Cryptococcus virulence factors, we assessed the virulence of the fbp4Δ, fbp11∆, fbp8Δ, and fbp4Δ fbp11Δ mutants in a murine inhalation model of systemic cryptococcosis.