Compared to lean or overweight DCM, the AUCs of CCDC80, NOX4, and COL1A2 dropped a lot in obese DCM and the control group, while HTRA1 (AUC = 0.9, p = 0.024) and KLHL29 (AUC = 0.8, p = 0.066) showed stable values within normal limits. This evidence concerns the gene CCDC80 and familial dilated cardiomyopathy.