The available formulas include: Cocroft-Gault, MDRD (Modification of Diet in Renal Disease), CKD –EPI creatinine (Chronic Kidney Disease Epidemiology Collaboration), CKD-EPI cystatin C, CKD-EPI creatinice-cystatine C. The cancer-specific GFR equations—such as Martin formula and Calvert formula were also developed. The gene discussed is CST3; the disease is kidney disorder.