It was reported that NLRs and PLRs have better diagnostic significance (p < 0.0001) for early-stage gastric cancer patients than the classical markers, such as CEA (carcinoembryonic antigen, cut-off value of 2.1, AUC (area under the curve) of 0.623; Sp of 70.59) and CA19-9 (carbohydrate antigen, cut-off value of 25.1, AUC of 0.565; Sp of 93.13), with a cut-off value of 2.25 for the NLR (AUC of 0.715; Sp of 83.04%) and 147.368 for PLR (AUC of 0.707; Sp of 81.79%). This evidence concerns the gene CEACAM5 and gastric cancer.