In treatment-naïve tumors, BiP positive staining was detected in 78.5% (11/14) of the samples, with them being predominantly cytosolic (72.4%) (Figure 6A) and was significantly correlated with HER2 expression (p-value = 0.046) and tumor grade (p = 0.014) (Table 7). Here, ERBB2 is linked to neoplasm.