However, they have described relation of promoter −909G > C polymorphism (rs85457) in PON1 with the severity of the stroke as the GG genotype was associated with a mild stroke [22], Grzegorzewska et al., has explored the three single nucleotide variants of PON1 in relation with cardiovascular mortality in conventional cigarette smokers and non-smokers treated with hemodialysis [35]. The gene discussed is PON1; the disease is Stroke.