Recent studies have found that salvianolic acid A can improve endothelial-mesenchymal transition in pulmonary vascular remodelling, inhibit inflammation and oxidative stress, and attenuate vascular remodelling in a pulmonary hypertension model by activating the Nrf2/HO-1 signalling pathway (Chen et al. This evidence concerns the gene HMOX1 and pulmonary arterial hypertension.