EZH2 and cancer: Given the essential role of EZH2 in the development and progression of cancer, therapeutic approaches targeting EZH2 have emerged as a promising approach for treating multiple cancer, such as inhibiting the activity of EZH2 methyltransferase, degradation of EZH2, breaking the structure of PRC2, and combining EZH2 inhibitors with other anticancer regimens [29–36].