There was also a significant relationship between urinary IL-18 levels ≥3.868 ng/ml with the occurrence of AKI in septic patients with p = 0.000, RR 20.078 (95% CI, 6.593–61.142) which means that septic patients with urinary IL-18 levels ≥3.868 ng/ml have a higher risk of AKI compared to urinary IL-18 <3.868 ng/ml. Here, IL18 is linked to acute kidney injury.