Studies on renal carcinoma cells 786-0 and ACHN (101), bladder cancer cell SW780 (102), oral cancer cell OC2 (103), three types of NPC cancer cells (104), hepatocellular carcinoma cell LM6 (105), fibrosarcoma cell HT1080 (106), lung cancer cell CL1-5 (107) showed that EGCG treatment downregulated mRNA or protein expression of MMP-2 or MMP-9, and decreased the ability of the cancer cells to metastasize. Here, MMP9 is linked to cancer.