ABCB1 and lip and oral cavity carcinoma: EGCG induced cisplatin-resistant oral cancer CAR cell autophagy in a time- and concentration-dependent manner, during which the AKT/signal transducer and activator of transcription 3 (STAT3) pathway was stimulated and the expression of multidrug resistance 1 (MDR1) was dose-dependently inhibited, suggesting the alteration of AKT/STAT3 signaling and downregulation of MDR1 were partially responsible for the EGCG-induced CAR cell autophagy and apoptosis (80).