At admission, the age, history of diabetes, blood glucose, plasma osmotic pressure, triglycerides, blood sodium, blood chloride, SCR, urea nitrogen, cystatin C, creatine kinase, troponin I, CRP, leukocytes, HCO3-, acute infection and deaths in the AOI group were significantly higher than those in the non-AOI group (Q <0.05), while blood ketone and serum albumin in the AOI group were unexpectedly significantly lower than those in the non-AOI group (Q <0.05). The gene discussed is CST3; the disease is diabetes mellitus.