Aicardi-Goutières syndrome (AGS) can be caused by mutations in the human three-prime repair exonuclease 1 (Trex1) gene, which is essential for DNA degradation and preventing cytoplasmic DNA accumulation (Gall et al., 2012; Gao et al., 2015). This evidence concerns the gene TREX1 and Aicardi-Goutières syndrome.