CD274 and neoplasm: Anti-PD-L1 treatment caused statistically significant decreases in the observed rates of tumor volume change in studies 3 and 4, but not in study 5 (p-values are unadjusted, significance threshold is 0.01/6 = 0.0016 with Bonferroni correction) despite the same dosing regimen being used in the studies and similar tumor sizes at treatment start in studies 3 and 5 (Supplementary Figure S2, Supplementary Table S2).