MACC1 mRNA expression was positively correlated with biomarkers of NK cells (CD56), M1 macrophages (TLR2 and IRF5), M2 macrophages (CD206, CD115, and Dectin-1), neutrophils (CD11b, CEACAM8, ITGAM and MPO), and dendritic cells (NRP1, ITGAX and CD83) in COAD (Table 3). The gene discussed is TLR2; the disease is colon adenocarcinoma.