In contrast, MACC1 expression was significantly lower in eight other types of cancer, namely adrenocortical carcinoma (ACC), HNSC, acute myeloid leukemia (LAML), LIHC, LUSC, pheochromocytoma and paraganglioma (PCPG), PRAD, and skin cutaneous melanoma (SKCM). Here, MACC1 is linked to prostate adenocarcinoma.