In general, dyslipidemia is characterized by high circulating concentrations of low-density lipoprotein-cholesterol (LDL-C), triglycerides (TGs), and apolipoprotein B (ApoB); and low circulating concentrations of high-density lipoprotein-cholesterol (HDL-C) and apolipoprotein A1 (ApoA1). The gene discussed is APOB; the disease is metabolic syndrome.