SOX7 and Neoplasm of the lung: In addition, Xia et al. (2015) and Wang et al. (2017a) demonstrated that downregulation of the expression level of MEG3 enhances cisplatin resistance of lung tumor cells by regulating the WNT/β-catenin signaling pathway and the miR-21-5p/SRY-box transcription factor 7 (SOX7) axis, respectively.