Relative tumor weight in the groups of anti-PD-L1, 4-1BB agonist, anti-PD-L1 plus 4-1BB agonist were 66.8 ± 7.5%, 52.2 ± 7.0% and 5.0 ± 4.6% respectively (Figure 1D). The gene discussed is CD274; the disease is neoplasm.