ssGSEA analysis showed that the infiltration of CD8+ T cell, DC (dendritic cell), pDC (plasmacytoid dendritic cells), Tfh (follicular T-helper-cell), Th1, TIL (tumor-infiltrating lymphocytes) and Treg was lower in the high-risk group, and APC (antigen-presenting cell) co-inhibition, cytolytic activity, inflammation-promoting, T cell functions such as co-inhibition and co-stimulation were attenuated (Figures 8C, D). The gene discussed is CD8A; the disease is neoplasm.