The dataset GSE15197 was normalized (Figures 1A, B), and m7G regulators were differentially analyzed in lung tissue samples from PAH patients and normal using the limma package, as shown in Figure 1C, 15 kinds of m7G regulators (NSUN2, DCP2, DCPS, NUDT11, NUDT16, NUDT3, CYFIP1, EIF4E, EIF4E2, NCBP1, EIF3D, EIF4A1, EIF4G3, IFIT5, and SNUPN) showed significant differences between PAH patients and Normal. This evidence concerns the gene IFIT5 and pulmonary arterial hypertension.