Importantly, given the neovascular AMD phenotype of the high‐risk RPE donors used in this study, angiogenesis linked brain acid soluble protein 1, EGF‐like repeat and discoidin I‐like domain‐containing protein 3 (EDIL 3) and aquaporin‐1 were also more abundant in the high‐risk RPE EVs (Figure 4C and Table S8). Here, BASP1 is linked to age-related macular degeneration.