Importantly, we are the first to identify three unique genes (e.g. KIF5A, PAQR6 and SLC1A3) that are associated with AD pathology (Fig. 8 and Additional file 1: Fig. S10) using transcriptomic methods, besides those genes identified by other groups [13, 16, 24, 60–64]. The gene discussed is SLC1A3; the disease is Alzheimer disease.