Regarding the associations of other CSF tau biomarkers with tau PET in the symptomatic AD group, p-tau181 and t-tau only associated with SUVR in the transentorhinal (corresponding to in vivo Braak I–II) composite region (p-tau181: ρ = 0.48, P < 0.05, t-tau: ρ = 0.47, P < 0.05), while p-tau217 was not associated with SUVR in any of the tau PET brain regions (Fig. 2D–L). This evidence concerns the gene MAPT and Alzheimer disease.