MAPT and Alzheimer disease: When using linear models to investigate whether these associations observed in the symptomatic AD group could be driven by Aβ pathology, we found that the relationship between tau368/t-tau and tau PET signal in limbic regions was not affected when amyloid PET SUVr was included in linear regression models (Table 2; corresponding tables for p-tau181, p-tau217, and t-tau are available in Supplementary Tables 3-5).