The 11 pathways are listed in CTD as being related to obesity, and eight pathways are also related to PCOS, including, including PI3K-Akt signaling pathway, hepatitis C, prion diseases, staphylococcus aureus infection, chagas disease (American trypanosomiasis), cytokine–cytokine receptor interaction, glutathione metabolism, and arachidonic acid metabolism. Here, AKT1 is linked to American trypanosomiasis.