In order to better clarify the molecular mechanism, biological function, and related signaling pathways of HERPUD1 in ovarian cancer, we conducted enrichment analysis of HERPUD1 and related genes by PPI, GO, and KEGG pathway analysis, and found that these genes are mainly involved in immune regulation, the assembly and transport of protein complexes in the ER, regulation of ERS, ubiquitin-dependent degradation, ERS-induced apoptosis, tumor metastasis, and other biological processes. The gene discussed is HERPUD1; the disease is ovarian cancer.