LGALS1 and acute myeloid leukemia: Results showed that combined treatment of LGALS1 inhibitor OTX008 and Ara-C significantly reduce the cell viability of AML cell line THP-1, MV-411, Kasumi-1, ME-1, HL-60, KG-1 and MOLM-13, compared with Ara-C alone (Fig. 8D and Supplementary Fig. S9).