LGALS1 and acute myeloid leukemia: As one of the most upregulated genes in QSCs cells in RR-AML (Fig. 2E and Supplementary Fig. S8), LGALS1 also showed a significantly increased expression in chemo-residual QSCs in refractory AML patients (Wilcoxon rank-sum test, p < 2.2e–16; Fig. 7A).