In the future, due to the prevalence of Atm, Pax5, Ebf1, Ikzf1, Ikzf3, Myc, Myb, and Trp53 mutagenesis in B cell lymphomas, it will be of special relevance to explore further how TIA1 and TIAL1 contribute to the post-transcriptional stabilization and translation of these mRNAs in both normal and cancer-transformed B cells. The gene discussed is IKZF3; the disease is cancer.