In peri-infarct tissue 7 days after subcortical white matter stroke, endothelial CXCL5 expression is significantly increased in mice on HFD versus those on CFD as measured by the percentage of CXCL5+ voxels that co-localized with GLUT-1 within the peri-infarct tissue surrounding the stroke (Figure 4F). Here, CXCL5 is linked to stroke disorder.