Considering that the triangulated interconnection of B-lineage cells is contributory to renal interstitial fibrosis, and that autoreactive PR3-positive B cells are pathophysiologically relevant in PR3-AAV, our data reveal an explicit degree of coherence since leukocyturia independently correlated with plasma cell infiltration, focal BCR and interstitial fibrosis in PR3-positive ANCA GN. Here, BCR is linked to ganglioneuroma.