ERBB2 and breast cancer: 111In[In]-BnDTPA-trastuzumab-NLS injection prepared from the kit described here was recently administered safely for the first time to 4 patients with HER2-positive BC to trace the uptake of trastuzumab into brain metastases, prior to and after application of MRI guided focused ultrasound (MRIg-FUS) (Meng et al. 2021).