We modified trastuzumab with diethylenetriaminepentaacetic acid (DTPA) to complex the MAE-emitter, 111In (t1/2 = 2.8 d) and subsequently conjugated these RICs to 13-mer peptides [CGYGPKKKRKVGG] that harboured the NLS of SV-40 large T-antigen (italics) to promote nucleus uptake after HER2-mediated internalization into BC cells (Costantini et al. 2007). Here, ERBB2 is linked to breast cancer.