The multiple effects of NLRP1 and NLRP3 are closely related to various human diseases associated with dysfunctional immunoregulation, including autoimmune diseases [12], asthma [13], psoriasis [14], lupus nephritis [15], and Alzheimer’s disease [16], and have also been reported to play crucial roles in tumor progression, prognosis, and treatment response [17–19]. Here, NLRP1 is linked to neoplasm.