SORCS2 and neurodegenerative disease: In thelist of MS-DAP exclusive hits just beyond the top-hits at0.1% FDR, we also observed proteins previously associated with AD.For instance, SorCS2 (q-value 0.002)belongs to the Vps10p-domain family of multiligandreceptors, and is implicated as genetic risk factor in sporadic andautosomal dominant forms of neurodegenerative diseases, includingAD.