HIF1A and epilepsy: Based on the above results, it can be speculated that the increase of HIF-1α expression after hypoxia-ischemia induced the increase of miRNA-210 expression, and miRNA-210 targeted to inhibit the expression of target genes, which led to the decrease of SCN1B expression and caused the decrease of SCN1B protein function, which in turn affected the normal function of ion channels and appeared abnormal discharge and other clinical symptoms such as abnormal muscle tone, convulsions, and even epilepsy.