LCN2 and acute kidney injury: Urinary biomarkers NGAL (neutrophil gelatinase‐associated protein), kidney injury molecule 1 (KIM‐1), and osteopontin (OPN) were shown to trend higher in neonates with AKI, as defined by a rise in serum creatinine (Askenazi et al., 2016; Rumpel et al., 2022).