Brain ischemia in young mice increased at day 4 the microglial mRNA expression of Adipophilin (Plin2), Perilipin (Plin3), Hypoxia‐Inducible Lipid Droplet‐Associated (Hilpda), granulin precursor (Grn), Abhydrolase Domain Containing 5, Lysophosphatidic Acid Acyltransferase (Abhd5), Synaptosome Associated Protein 23 (Snap23), and lipoprotein lipase (Lpl; Fig 2A). Here, PLIN2 is linked to brain ischemia.