Analyzing this hypothesis, the comorbidities data in the age groups revealed that the percentage of obesity is high in all age groups (19.6% in adolescents and young adults, 45.5% in adults, and 31.2% in seniors) and this probably was not the main factor that influenced the high IgA production. The gene discussed is CD79A; the disease is obesity due to melanocortin 4 receptor deficiency.