CD79A and obesity due to melanocortin 4 receptor deficiency: These comorbidities, especially obesity, were described to have a high baseline of pro-inflammatory cytokines and SARS-CoV-2 infection could have a stimulatory effect on humoral response, which culminates here with the observation of high IgA production in these patients (Ejaz et al., 2020; Kulcsar et al., 2019).