TNKS2 and acute myeloid leukemia: For instance, miR-582-5p suppresses the growth and invasion of osteosarcoma cells through targeting NOVA1 [11], inhibits bladder cancer-genesis through downregulating TTK expression [12], serves as an antioncogenic biomarker in acute myeloid leukemia (AML), hinders leukemia cell proliferation, induces cell apoptosis [13], and also hampers the migration and chemoresistant capabilities of colorectal cancer cells through targeting TNKS2 [14].